5. TE James Mitchell
Mitchell only played six snaps against the Chiefs, as rookie Sam LaPorta naturally (and expectedly) took the reigns as the Lions' No. 1 tight end. But the second-year man still earned a dismal grade from Pro Football Focus (59.5, fifth-worst among Lions' offensive players) and got zero targets. Brock Wright also significantly out-snapped him (27 to 6).
Even with LaPorta as the clear TE1 for the Lions, Mitchell shouldn't have much trouble taking over more of the snap allocation between he and Wright. Week 1 can go down as a mulligan, now set to go against a Seahawks' defense that is generous to tight ends.
4. Edge James Houston
Houston was not noticeable against Kansas City, albeit over just 21 defensive snaps (zero tackles, one quarterback hit). But Seattle is going to be down at least one (right tackle Abraham Lucas on IR) if not both (left tackle Charles Cross, who suffered a toe injury in Week 1) of their starting offensive tackles. Apart from the clear talent drop-off, inexperienced Seahawks' tackles will also have to deal with the noise inside Ford Field.
The Lions need someone to step up opposite Aidan Hutchinson, as he'll surely command rampant double-teams on Sunday. Houston is as good a candidate as anyone to have a breakthrough performance, in the second game of his second season. The opportunity to re-assert himself should be right in front of him.