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Lions vs. Panthers Week 4 tracker: Injury updates, prediction, storylines, and more

Detroit is headed south for a Sunday Night Football matchup with the Panthers.
ByCandace Pedraza
Detroit Lions quarterback Jared Goff (16) celebrates the touchdown with Detroit Lions wide receiver Amon-Ra St. Brown (14) during the first half of the NFL game at Ford Field in Detroit, Sunday, Sept. 27, 2026.
Detroit Lions quarterback Jared Goff (16) celebrates the touchdown with Detroit Lions wide receiver Amon-Ra St. Brown (14) during the first half of the NFL game at Ford Field in Detroit, Sunday, Sept. 27, 2026. | USA TODAY Network via Reuters Connect

The Detroit Lions are headed south for a Sunday Night Football game against the Carolina Panthers. It's wild to think that it's already Week 4, but we're already stumbling into the colder months and into a very contentious portion of the Lions' schedule.

After this Panthers game and their Week 5 bout against the Arizona Cardinals on the road, they'll have a bye week followed by back-to-back NFC North games. We're already hitting that point in the year, when regular season games matter a little more.

Ahead of that time, though, we'll take a look at the Lions' impending matchup against the Panthers, who are set to be very undermanned for this contest. For once, the Lions don't seem primed to be the more injured team.

Last updated: Thursday, October 1, 9:30am

  1. Lions, Panthers injury tracker for Week 4
  2. Storylines to follow between Lions and Panthers in Week 4
  3. Prediction

Lions, Panthers injury tracker for Week 4

Lions injuries

Player

Injury

Wednesday, September 30

OL Ben Bartch

Foot

NP

DJ Wonnum

Back

NP

CB D.J. Reed

Rib

LP

Panthers injuries

Player

Injury

Wednesday, September 30

WR Jalen Coker

Quad

NP

WR Xavier Legette

Knee

NP

LG Damien Lewis

Elbow

NP

RT Monroe Freeling

Concussion

NP

TE Darren Waller

Rest/toe

NP

RB Chuba Hubbard

Not injury related

NP

QB Bryce Young

Knee

FP

LB Princely Umanmielen

Ankle

NP

LB Devin Lloyd

Calf

FP

S Nick Scott

Ribs

FP

In addition to all the above reported injuries for the Panthers, they placed both of their starting cornerbacks - Jaycee Horn and Mike Jackson - on the IR ahead of this game. That's a huge blow to their pass defense, which has had a decent start to the season. With that lack of resistance in the air coupled with their poor run defense, this game could get ugly fast.

The Lions' injury report from Wednesday was short - the only concerning players on their list are Wonnum and Reed. Head coach Dan Campbell did not indicate that either would be missing time or this game in his Wednesday press availability, though.

Storylines to follow between Lions and Panthers in Week 4

Can Detroit take advantage of Carolina's injury woes?

The Lions are typically on the other end of this formula, so it's strange to be thinking about how they can take advantage of the Panthers' weaknesses in Week 4. As mentioned, they'll be without their starting cornerbacks in Week 4, and that could create more opportunities for players like Jameson Williams, Amon-Ra St. Brown, Isaac TeSlaa, and Sam LaPorta.

Of course, Lloyd may be back for this game, so that could make things difficult for Detroit's tight end room at the very least. And, it could help Carolina to improve upon their run defense - they're allowing a league-high 193.3 rushing yards per game, which feels like a D-line stat and a linebacker stat, for sure.

Jahmyr Gibbs is likely to still get a ton of touches in this game despite those weaknesses worth poking in the Panthers' secondary, but it'll likely result in good things for Detroit's offense.

More Isaac TeSlaa touches?

Lions wide receivers coach Scottie Montgomery told reporters on Wednesday that he's liked the process so far with Jameson Williams this season, and specifically mentioned how nice it's been that teams are doubling him downfield. As a result, it's leaving players like LaPorta, TeSlaa, and St. Brown in one-on-one competitions that are resulting in separation and catches.

“If you choose to double he and St. (Brown), then you get one-on-one matchups with (LaPorta, Gibbs, TeSlaa).”

The Lions have a ton of weapons to utilize in their offense, and despite scoring 31 points in three straight games to open up their season, it still feels like they're missing opportunities to break games open. Providing more looks to someone like TeSlaa, who has proven to be a threat downfield and in the red zone, could open things up even further for their offense. He finished up Week 3 with 66 receiving yards on three targets.

Lions' pass rush could go off vs. Panthers

As mentioned, injuries have ravaged the Panthers as of late, but mostly on their defense. Still, one key injury has hit their offensive line that's worth mentioning: their left guard, Damien Lewis, is likely out of this game with a PCL injury.

Carolina is currently ranked 25th in pass block win rate, and while Young is a mobile quarterback, he's no Josh Allen. Failing to protect him could open the floodgates for Aidan Hutchinson, Alim McNeill, and DJ Wonnum to get him on the ground and throw him off his base, and to potentially generate some turnovers as a result.

Wonnum popped up on the injury report on Wednesday ahead of the game, but again, there has been no indication from the Lions that he might miss this game. Detroit's defensive line has shown up this year, at the very least, helping to mask their major woes in their secondary.

First game post-Porter trade

A microscope is certain to be on Ennis Rakestraw Jr., Roger McCreary, and anyone else the Lions toss out at CB2 in this game after they failed to acquire Joey Porter Jr. from the Pittsburgh Steelers. As I wrote following the trade, though, it doesn't really feel like a failure on the Lions' part - money, a culture fit, and a likely unwillingness to part with a 2nd-round pick all combined to make this sort of deal unlikely.

Still, however unfairly, Detroit's solution(s) at the position are now set to be scrutinized until they land a legitimate starter there - if they do at all. Rakestraw, especially, is bound to have some extra eyes on him. The 2024 draft pick had promising snaps against the New York Jets in Week 3, and he earned another look in Week 4 against an injured Panthers team that could be without WR1 Jalen Coker.

Prediction

I have to go with the Lions in this game, mostly because of how injured the Panthers are on defense. Detroit's offense is a problem regardless, but with less resistance by way of Horn and Jackson, they'll be even more open to let it fly downfield. That, coupled with their offensive line shaping up to be even stronger than they were to kick off the year, feels like a perfect recipe for an offensive explosion.

Assuming Coker doesn't go in this game, too, the Lions will have one less target for Young to have to worry about defending closely. Obviously, this doesn't fully eliminate the Panthers as a threat on offense - the team will have to still contain Hubbard, and Tet McMillan - but you like the Lions' chances of successfully doing that over Carolina's chances of containing Detroit.

I'll go with a final score of 31-27 here.

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