Sep 15, 2013; Phoenix, AZ, USA; Arizona Cardinals wide receiver Larry Fitzgerald (11) completes a pass thrown by quarterback Carson Palmer (not pictured) in the third quarter against the Detroit Lions at University of Phoenix Stadium. Mandatory Credit: Jennifer Hilderbrand-USA TODAY Sports

Detroit Lions Final Score: Cardinals Win it 25-21

Arizona Cardinals 25, Detroit Lions 21 (box score)

Nothing good ever seems to happen for the Detroit Lions when they have to travel to the desert to play the Arizona Cardinals.

It seemed like the Lions would have a chance to change that, controlling much of the game. But missed opportunities and a lack of a killer instinct cost the Lions the opportunity to start the season 2-0.

The Lions left points on the field in the form of two botched field goal opportunities. David Akers missed a 52-yard field goal but got another shot from 47 after the Cardinals were called for running into the kicker. Instead of missing to the left, Akers missed this one ot the right. Still, the Lions took a 14-10 lead into the half.

Had it not been for a DeAndre Levy interception returned for a touchdown the third quarter would have been a total disaster. The Cardinals controlled the clock with Matthew Stafford unable to complete a single pass in his limited opportunities in the quarter. As bad as it was, the Lions defense held the Cardinals to field goals, allowing the Lions to hold a 21-16 lead after three quarters of play.

After the Cardinals opened the fourth with a field goal to cut the lead to 21-19, the Lions put together a 51-yard drive to put them in position to get the points right back. But Akers’ 47-yard field goal attempt was blocked.

After trading punts, the Cardinals marched down the field looking for the go-ahead score. On the Lions 32-yard line they faced a third down but drew a big pass interference penalty on Bill Bentley that put the ball on the one yard line. Rashard Mendenhall took it in two plays later for the winning score.

With 1:59 and timeouts in hand, the Lions had plenty of time to mount their own winning drive but that opportunity was lost when Nate Burleson caught a two yard pass on a fourth and four play.

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